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Interesting how they call this child a “boy” if the karyotype and genitalia are so ambiguous. Like, why???
A three years old apparently male child was referred to Anhui Provincial hospital with a complaint of undifferentiated external genitalia.
It might just be that that’s what they’re registered as, or how parents referred to them, I guess?
nobody called me on this actually being karyotypes and not genotypes. I’m disappointed
Ambiguous Genitalia would make a good pub quiz team name.
The Novel Sex Chromosomes was the name of my college marching band
45,X/46,XX, 45,X/46,XY and 46,XY/47,XXY was my locker combination in high school!
Is YY possible though? Never heard of that one.
If YY happens, the fetus will not form normally and you will probably have at best a miscarriage
You can be XYY and doctors will shorten that informally to YY. https://www.webmd.com/a-to-z-guides/what-are-yy-chromosomes
I see. That makes sense.
I think it’s not, since the X chromosome contains vital genes while the Y chromosome kinda does nothing. If you don’t have an X chromosome, you should be missing important genes. I might be wrong though.
I heard about XYY, XXY and even XXX so was wondering about this one. Since it’s still 50/50 (more or less) and it has to contain at least one X, I would guess. Still confused by the article title though.
YY is not possible in isolation because you need at least an X chromosome to survive as stated above, however! this article is about someone with extreme mosaicism, meaning that some of his cells don’t have the same chromosomes as the rest of his body, so some of his cells are YY but other parts of his body have X chromosomes so it’s still survivable overall
Wow, so kinda like chimerism? Though this is on another level. Couldn’t find a wiki page but definitely would like to read about it. By the way, while searching for this, I found about XXYY which I also didn’t know about.
Monotremes possess 5X and Ys, but their system is more related to birds and reptiles ZW,
Normally no, since one gonosome comes from each parent: The mother (XX) and the father (XY).
If somehow a series of unfortunate meioses occurred to create a zygote that had two Y chromosomes and no X chromosome, the foetus would absolutely not be viable, since the X chromosome contains many essential genes, while the Y chromosome is a truncated version that has less than half the information
There are situations that occur during fertilization, if the egg somehow loses it genetic material, the sperm enters the egg, but it duplicates its own half genome to form a 46 pairs but this is abnormal, because the gene pattering and also epigenetic silencing is different from males and females, so it forms abnormal mass of tissue called a mole; it can be partial or complete, one of the types can become a rare form of cancer
TIL meiosis gone wrong can cause a cumshot to give you cancer.
Thanks, internet stranger!
